发明名称 |
DESATURASE GENES AND USES THEREOF |
摘要 |
The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., " DELTA 5-desaturase") and at carbon 6 (i.e., " DELTA 6-desaturase") and to uses thereof. In particular, DELTA 5-desaturase may be utilized, for example, in the conversion of dihomo-g-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20: 4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to g-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics. |
申请公布号 |
EP1392823(A2) |
申请公布日期 |
2004.03.03 |
申请号 |
EP20020736480 |
申请日期 |
2002.01.24 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
MUKERJI, PRADIP;HUANG, YUNG-SHENG;DAS, TAPAS;THURMOND, JENNIFER;PEREIRA, SUZETTE, L. |
分类号 |
A01H5/00;A61K31/232;A61P3/00;A61P3/10;A61P9/10;A61P11/06;A61P13/12;A61P17/02;A61P17/06;A61P17/14;A61P17/16;A61P19/02;A61P19/10;A61P29/00;A61P35/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/02;C12N15/09;C12N15/82;C12P7/64 |
主分类号 |
A01H5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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