发明名称 Thiol compounds, their production and use
摘要 The present invention provides a compound represented by Formula:wherein ring A and ring B may be same or different and each is an optionally substituted homocyclic or heterocyclic ring and the like, each R<1 >may be same or different and is a hydrogen atom, an optionally substituted hydrocarbon group, an acyl group, an optionally substituted heterocyclic group or SR<2>, etc., X<1 >is a bond, an optionally substituted divalent C1-3 aliphatic hydrocarbon group or -NR<3>-, etc, X<2 >is a bond, an optionally substituted divalent C1-3 aliphatic hydrocarbon group, -NR<4>-, -O- or -S(O)p- (wherein p is 0, 1 or 2), each Y may be same or different and is a hydrogen atom, an optionally substituted hydrocarbon group, a halogen atom, a carboxyl group, an acyl group, an optionally substituted hydroxy group, an optionally substituted amino group, SR<5>, an oxo group, a thioxo group, an optionally substituted imino group, a nitro group, a cyano group, etc., each m may be same or different and is 0 or 1, n is an integer of 1 to 3, q1 is an integer of 1 to 2n+4, q2 is an integer of 0 to 2n+3, and the sum of q1 and q2 is 2n+4 or a salt thereof.
申请公布号 US6699881(B2) 申请公布日期 2004.03.02
申请号 US20020161289 申请日期 2002.06.03
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 YAMASHITA TOSHIRO;NARA HIROSHI;TAKIZAWA MASAYUKI;YOSHIMURA KOJI
分类号 A61P19/02;A61P19/10;C07D207/26;C07D207/273;C07D207/40;C07D207/416;C07D209/48;C07D211/76;C07D211/78;C07D211/88;C07D401/12;C07D403/12;C07D405/06;C07D405/12;C07D409/12;(IPC1-7):C07D211/98;C07D207/50;A61K31/452;A61K31/402 主分类号 A61P19/02
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