发明名称 |
Modified sFv molecules which mediate adhesion between cells and uses thereof |
摘要 |
The modified sFv molecules of the present invention stimulate adhesion between cells thereby enhancing the immune response against disease. These molecules generally comprise an antigen binding site of an antibody and at least a portion of a transmembrane domain of a cell surface receptor.
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申请公布号 |
US6699715(B1) |
申请公布日期 |
2004.03.02 |
申请号 |
US19960756416 |
申请日期 |
1996.11.27 |
申请人 |
BRISTOL-MYERS SQUIBB CO. |
发明人 |
LEDBETTER JEFFREY A.;HAYDEN MARTHA;FELL PERRY;MITTLER ROBERT;WINBERG GOSTA |
分类号 |
C07K14/705;C07K16/28;C07K16/30;(IPC1-7):A61K39/395;C07K16/46;C12N5/10 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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