发明名称 |
Identification of new therapeutic targets for modulating bile acid synthesis |
摘要 |
Abstract: Methods for identifying compounds that modulate bile acid synthesis by assessing their ability to act as ligands for short heterodimerizing partner-1 or liver receptor homologue-1 are provided. Also provided are compositions containing these ligands as well as methods for administering these compositions to modulate bile acid synthesis and cholesterol and lipid homeostasis.
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申请公布号 |
US2004038862(A1) |
申请公布日期 |
2004.02.26 |
申请号 |
US20030343289 |
申请日期 |
2003.01.28 |
申请人 |
GOODWIN BRYAN JAMES;JONES STACEY ANN;KLIEWER STEVEN ANTHONY;MALONEY PATRICK REED |
发明人 |
GOODWIN BRYAN JAMES;JONES STACEY ANN;KLIEWER STEVEN ANTHONY;MALONEY PATRICK REED |
分类号 |
G01N33/566;(IPC1-7):G01N33/53;A61K38/17;G01N33/567 |
主分类号 |
G01N33/566 |
代理机构 |
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