发明名称 SOLUBLE STABLE PHARMACEUTICAL COMPOSITION FOR THE ADMINISTRATION OF HIV PROTEASE INHIBITORS AND A PROCESS FOR THE PREPARATION OF CONCENTRATED PHARMACEUTICAL COMPOSITIONS FOR THE ADMINISTRATION OF HIV PROTEASE INHIBITORS.
摘要 The present invention describes a soluble stable pharmaceutical composition for the administration of HIV protease inhibitors. More specifically the composition comprises a solution of an HIV protease inhibitor in a combination of suitable pharmaceutical organic solvents, a surfactant and a bioavailability enhancer. It is also described a process for the obtainment of concentrated pharmaceutical compositions used in the administration of HIV protease inhibitors compounds. The composition of the present invention is suitable for the preparation of oral solutions for the administration of active drugs and for the encapsulation in hard gelatin capsules or soft gelatin capsules.
申请公布号 WO03105826(A3) 申请公布日期 2004.02.19
申请号 WO2003BR00076 申请日期 2003.06.12
申请人 CRISTALIA PRODUTOS QUIMICOS FARMACEUTICOS LTDA.;PACHECO, OGARI;RUSSO, ELISA;RUSSO, VALTER 发明人 PACHECO, OGARI;RUSSO, ELISA;RUSSO, VALTER
分类号 A61K9/00;A61K31/225;A61K47/10;A61K47/14;A61K47/22;A61K47/44 主分类号 A61K9/00
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