发明名称 |
ASPERTOKINASEGENVARIANTEN |
摘要 |
A transformant with an increased rate of L-lysine production and secretion is obtained by introducing into a corynebacterium a recombinant DNA that can be replicated in a corynebacterium and contains either a DNA fragment originating in a corynebacterium and coding for an aspartokinase alpha -subunit protein whereby a synergistic feedback inhibition by L-lysine and L-threonine is released or a DNA fragment originating in a corynebacterium and coding for an aspartokinase beta -subunit protein whereby a synergistic feedback inhibition by L-lysine and L-threonine is released. The obtained transformant is cultured in a suitable medium and the formed L-lysine is separated. <MATH> |
申请公布号 |
DE69332805(T2) |
申请公布日期 |
2004.02.19 |
申请号 |
DE1993632805T |
申请日期 |
1993.12.14 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
SUGIMOTO, MASAKAZU;OGAWA, YURI;SUZUKI, TOMOTO;TANAKA, AKIKO;MATSUI, HIROSHI |
分类号 |
C12N9/12;C12N15/09;C12N15/54;C12P13/08;C12R1/13;C12R1/15 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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