发明名称 Adenovirus formulations
摘要 The invention relates to viral formulations and related pharmaceutical products for use in gene therapy and/or vaccine applications. Especially preferred viral formulations disclosed herein are liquid adenovirus formulations, which show improved stability when stored in about the 2-8° C. range while also being compatible with parenteral administration. These formulations comprise a buffer, a sugar, a salt, a divalent cation, a non-ionic detergent, as well as a free radical scavenger and/or a chelating agent to inhibit free radical oxidation.
申请公布号 US2004033239(A1) 申请公布日期 2004.02.19
申请号 US20020204388 申请日期 2002.08.20
申请人 EVANS ROBERT K;VOLKIN DAVID B 发明人 EVANS ROBERT K;VOLKIN DAVID B
分类号 A61K39/00;A61K39/235;A61K48/00;C12N15/861;(IPC1-7):A61K39/23 主分类号 A61K39/00
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