发明名称 |
TYROSINE KINASE INHIBITORS |
摘要 |
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and n on- receptor type tyrosine kinases. The compounds of the instant invention posse ss a core structure that comprises a sulfonyl indole moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
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申请公布号 |
CA2494962(A1) |
申请公布日期 |
2004.02.19 |
申请号 |
CA20032494962 |
申请日期 |
2003.08.05 |
申请人 |
MERCK & CO., INC. |
发明人 |
DINSMORE, CHRISTOPHER J.;LINDSLEY, CRAIG W.;BESHORE, DOUGLAS C.;BERGMAN, JEFFREY M. |
分类号 |
C07D487/10;A61K31/138;A61K31/337;A61K31/40;A61K31/404;A61K31/407;A61K31/438;A61K31/44;A61K31/4465;A61K31/4535;A61K31/454;A61K31/4545;A61K31/495;A61K31/496;A61K31/5377;A61K31/541;A61K31/547;A61K31/55;A61K31/551;A61K31/553;A61K39/395;A61K45/00;A61P1/04;A61P3/10;A61P27/02;A61P35/00;A61P37/02;A61P43/00;C07D;C07D209/02;C07D209/42;C07D209/96;C07D211/02;C07D215/02;C07D267/02;C07D401/04;C07D401/12;C07D401/14;C07D403/02;C07D403/04;C07D403/12;C07D405/04;C07D405/12;C07D409/04;C07D413/02;C07D413/04;C07D413/12;C07D413/14;C07D417/04;C07D417/12;C07D417/14;C07D451/02;C07D491/04;C07D491/048;C07D491/08;C07D491/10;C07D491/107;C07D491/12;C07D498/04;C07D513/04;C07D513/08;(IPC1-7):C07D267/02 |
主分类号 |
C07D487/10 |
代理机构 |
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