发明名称 Treatment methods of inflammatory and immune diseases by making use of IkB kinase inhibitors (IKK)
摘要 <p>The present invention describes methods of preventing and treating inflammatory and immune-related diseases or disorders using inhibitors of I kappa B kinase (IKK). Also described are IKK inhibitors effective for the prevention and treatment of inflammatory and immune-related diseases or disorders, as demonstrated in vivo. Further embodiments of the present invention relate to a specific IKK inhibitors, 4(2'-aminoethyl)amino- 1,8-dimethylimidazo(1,2-a) quinoxaline and compounds of formula (I), salts thereof, and pharmaceutical compositions.</p>
申请公布号 CZ20032287(A3) 申请公布日期 2004.02.18
申请号 CZ20030002287 申请日期 2002.02.01
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 BURKE JAMES R.;NADLER STEVEN;QIU YUPING;TOWNSEND ROBERT M.;ZUSI FRED CHRISTOPHER
分类号 C07D487/04;A61K31/4985;A61K31/519;A61K38/22;A61K45/00;A61P1/04;A61P9/00;A61P9/02;A61P9/10;A61P11/00;A61P11/06;A61P17/02;A61P17/04;A61P19/02;A61P25/00;A61P25/16;A61P25/28;A61P27/16;A61P29/00;A61P37/00;A61P37/06;A61P41/00;A61P43/00;C12N1/21;C12N15/54;(IPC1-7):A61K31/474;A61K38/43;A61K31/517 主分类号 C07D487/04
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