| 发明名称 |
Humanized antibodies against human 4-1bb |
| 摘要 |
A humanized antibody that binds to human 4-1BB and that allows binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating cancer in a subject comprising administering a therapeutically effective amount of the antibody to said subject. |
| 申请公布号 |
AU2003259294(A8) |
申请公布日期 |
2004.02.16 |
| 申请号 |
AU20030259294 |
申请日期 |
2003.07.30 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
DIANE L. HOLLENBAUGH;BARBARA THORNE;SUBINAY GANGULY;ROBERT S. MITTLER;WALTER W. SHUFORD;MARIA JURE-KUNKEL;RALPH ABRAHAM;JILL RILLEMA |
| 分类号 |
A61K;A61K39/395;A61P35/00;C07H21/04;C07K16/28;C12N15/13;C12P21/08;(IPC1-7):A61K39/395 |
主分类号 |
A61K |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
