发明名称 METHOD FOR TREATING GOUT AND BINDING URIC ACID.
摘要 <p>A method for treating gout and/or reducing serum uric acid levels in a patient is disclosed that includes administering to the patient a therapeutically effective amount of an amine polymer, for example, an aliphatic amine polymer. In one embodiment, the polymer binds to uric acid or a precursor thereof. Examples of polymers useful in an embodiment of the invention include sevelamer hydrochloride and colesevelam. The invention includes the use of amine polymers such as a cross-linked polymer characterized by a repeat unit having the formula: and salts and copolymers thereof, where n is a positive integer and x is zero or an integer between 1 and about 4. Also described is a use, for the manufacture of a medicament, of a polymer that binds serum uric acid in a patient.</p>
申请公布号 MXPA03009571(A) 申请公布日期 2004.02.12
申请号 MX2003PA09571 申请日期 2002.04.10
申请人 GENZYME CORPORATION 发明人 STEPHEN RANDALL HOLMES-FARLEY
分类号 A61K45/00;A61K31/519;A61K31/78;A61K31/785;A61K31/787;A61P3/00;A61P13/02;A61P13/12;A61P19/06;(IPC1-7):A61K31/785 主分类号 A61K45/00
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