发明名称 |
Combination treatment with t-PA variant and low molecular weight heparin |
摘要 |
The invention concerns an improved therapeutic regimen for the treatment of thrombolytic disorders, such as acute myocardial infarction (AMI). In particular, the present invention concerns the treatment of thrombolytic disorders, e.g. AMI, with a combination of a tissue plasminogen activator (t-PA) variant having improved fibrin specificity and extended plasma half-life when compared with wild-type human t-PA and a low molecular weight heparin.
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申请公布号 |
US2004029798(A1) |
申请公布日期 |
2004.02.12 |
申请号 |
US20030371778 |
申请日期 |
2003.02.21 |
申请人 |
ARMSTRONG PAUL;BARRON HAL;BERIOLI SILVANO;BIGONZI FREDERIQUE;BLUHMKI ERICH;CHIN RICHARD;GRANGER CHRISTOPHER;WERF FRANS VAN DE;WANG-CLOW FONG |
发明人 |
ARMSTRONG PAUL;BARRON HAL;BERIOLI SILVANO;BIGONZI FREDERIQUE;BLUHMKI ERICH;CHIN RICHARD;GRANGER CHRISTOPHER;WERF FRANS VAN DE;WANG-CLOW FONG |
分类号 |
A61K38/49;(IPC1-7):A61K38/17 |
主分类号 |
A61K38/49 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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