发明名称 |
Solvates and polymorphs of ritonavir and methods of making and using the same |
摘要 |
Novel solvates and crystal polymorphs of Ritonavir are disclosed, as well as methods of making them. Specific solvates of the compound include a formamide solvate and a partially desolvated solvate. Also disclosed are methods of making previously known forms of Ritonavir. Methods of using the novel forms of Ritonavir for the treatment of diseases, such as HIV-infection, are disclosed, as are pharmaceutical compositions and unit dosage forms comprising the novel forms of Ritonavir.
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申请公布号 |
US2004024031(A1) |
申请公布日期 |
2004.02.05 |
申请号 |
US20030427607 |
申请日期 |
2003.05.01 |
申请人 |
TRANSFORM PHARMACEUTICALS INC |
发明人 |
MORISSETTE SHERRY L;ALMARSSON ORN;SOUKASENE STEPHEN |
分类号 |
A61K31/427;A61K45/06;C07D277/28;(IPC1-7):A61K31/427;C07D417/02 |
主分类号 |
A61K31/427 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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