| 发明名称 |
Modified proinsulin variants and composition containing same |
| 摘要 |
IGF-I and insulin variants are provided that selectively bind to IGFBP-1 or IGFBP-3. These agonist variants are useful, for example, to improve the half-lives of IGF-I and insulin, respectively.
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| 申请公布号 |
US2004023883(A1) |
申请公布日期 |
2004.02.05 |
| 申请号 |
US20030444262 |
申请日期 |
2003.05.22 |
| 申请人 |
DUBAQUIE YVES;LOWMAN HENRY |
发明人 |
DUBAQUIE YVES;LOWMAN HENRY |
| 分类号 |
C12N15/02;A61K38/00;A61K38/27;A61P1/14;A61P3/04;A61P3/08;A61P3/10;A61P5/02;A61P5/38;A61P5/44;A61P5/48;A61P5/50;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P11/16;A61P13/12;A61P15/00;A61P15/08;A61P17/00;A61P17/02;A61P19/00;A61P19/04;A61P19/10;A61P21/00;A61P21/04;A61P25/00;A61P25/02;A61P25/18;A61P25/24;A61P25/28;A61P31/18;A61P35/00;A61P37/00;A61P37/04;A61P41/00;A61P43/00;C07K14/62;C07K14/65;C12N15/09;(IPC1-7):A61K38/28;C12P21/02;C12N5/06 |
主分类号 |
C12N15/02 |
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