| 发明名称 |
MATERIALS AND METHODS FOR TREATING HYPERCHOLESTEROLEMIA |
| 摘要 |
The subject invention provides novel HMG-CoA-reductase inhibitors. In a preferred embodiment, the HMG-CoA reductase inhibitors of the subject invention can be deactivated to a primary inactive metabolite by hydrolytic enzymes. Compounds of the present invention can be advantageously used to treat patients suffering hypercholesterolemia.
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| 申请公布号 |
CA2492906(A1) |
申请公布日期 |
2004.01.29 |
| 申请号 |
CA20032492906 |
申请日期 |
2003.07.21 |
| 申请人 |
ARYX THERAPEUTICS, INC. |
发明人 |
DRUZGALA, PASCAL;ZHANG, XIAOMING |
| 分类号 |
A61K31/22;A61K31/343;A61K31/353;A61K31/40;A61K31/404;A61K31/4418;A61K31/47;A61K31/505;A61K31/56;A61K31/573;A61K31/575;A61P3/06;A61P43/00;C07C69/675;C07C69/708;C07C69/732;C07D207/34;C07D209/12;C07D209/18;C07D209/24;C07D209/42;C07D213/30;C07D213/55;C07D213/80;C07D215/12;C07D215/14;C07D239/42;C07D307/79;C07D307/80;C07D311/72;C07J3/00;C07J5/00;C07J9/00;(IPC1-7):C07C69/675;C07D209/10 |
主分类号 |
A61K31/22 |
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