发明名称 Indolylpiperidine derivatives as antihistaminic and antiallergic agents
摘要 Indolylpiperidine compounds of formula (I)wherein:A<1 >represents an alkylene, alkyleneoxy, alkylenethio, alkanoyl or hydroxyalkylene group;A<2 >represents a single bond, an alkylene or alkenylene group;W represents a single bond or a phenylene or furanylene group which is unsubstituted or substituted by one or more halogen atoms, alkoxy groups and/or alkyl groups;R<2 >represents a hydrogen or halogen atom or an alkyl or alkoxy group; andR<3 >represents a carboxyl group or a tetrazolyl group.The present invention provides novel indolylpiperidine compounds having imporved antihistamine and antiallergic activity.
申请公布号 US6683096(B2) 申请公布日期 2004.01.27
申请号 US20010006416 申请日期 2001.12.04
申请人 ALMIRALL PRODESFARMA, S.A. 发明人 PAGES SANTACANA LLUIS;FONQUERNA POU SILVIA;PUIG DURAN CARLES;FERNANDEZ FORNER MARIA DOLORS
分类号 A61K31/445;A61K31/4525;A61K31/454;A61P11/02;A61P11/04;A61P11/06;A61P27/02;A61P37/08;C07D401/04;C07D401/14;C07D405/14;(IPC1-7):A61K31/445 主分类号 A61K31/445
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