| 发明名称 |
Double-stranded oligonucleotides |
| 摘要 |
Antisense sequences, including duplex RNAi compositions, which possess improved properties over those taught in the prior art are disclosed. The invention provides optimized antisense oligomer compositions and method for making and using the both in in vitro systems and therapeutically. The invention also provides methods of making and using the improved antisense oligomer compositions.
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| 申请公布号 |
US2004014956(A1) |
申请公布日期 |
2004.01.22 |
| 申请号 |
US20030357529 |
申请日期 |
2003.02.03 |
| 申请人 |
SEQUITUR, INC. |
发明人 |
WOOLF TOD M.;WIEDERHOLT KRISTIN A. |
| 分类号 |
C12N15/09;A61K31/713;A61K48/00;A61P1/04;A61P9/00;A61P17/06;A61P27/02;A61P29/00;A61P31/12;A61P31/18;A61P31/20;A61P35/00;A61P37/02;A61P43/00;C07H19/00;C07H21/02;C07H21/04;C12N;C12N15/00;C12N15/113;(IPC1-7):C07H21/02 |
主分类号 |
C12N15/09 |
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