Cyclothiocarbamate derivatives as progesterone receptor modulators and methods of treating skin disorders

摘要

The present invention provides methods of treating skin disorders includes delivering to a mammal a composition containing a compound of formula I, or tautomers thereof, in a regimen, wherein formula I is: and wherein R<1>-R<5 >and Q<1 >are defined as described herein. Specifically, methods for treating acne, hirsutism, and conditioning the skin are described. Also provided are novel PR modulators of formula II.