| 发明名称 |
ANTISENSE INHIBITION VIA RNASE H-INDEPENDENT REDUCTION IN MRNA |
| 摘要 |
<p>The present invention provides compositions and methods for reducing levels of a preselected mRNA, using antisense compounds targeted to a splice site on said mRNA. Preferably, said antisense compounds do not elicit RNAse H cleavage of the mRNA.</p> |
| 申请公布号 |
AU2003247521(A1) |
申请公布日期 |
2004.01.19 |
| 申请号 |
AU20030247521 |
申请日期 |
2003.06.12 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
BRETT, P. MONIA;SUSAN, M. FREIER;MUTHIAH MANOHARAN;WILLIAM, A. GAARDE |
| 分类号 |
A61K38/00;C12N15/113 |
主分类号 |
A61K38/00 |
| 代理机构 |
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