摘要 |
<p>The invention relates to a isoindole-imide compound of formula I-4 comprising compound. The compound I-4 is a potent inhibitor of the production of the TNF-± in mammals, and thus useful for treating or preventing diseases or disorders in mammals, for example, cancers, such as solid tumors and blood-born tumors; heart disease, such as congestive heart failure; osteoporosis; and genetic, inflammatory, allergic, and autoimmune diseases.</p> |