发明名称 |
IMPLANTABLE OR INSERTABLE MEDICAL DEVICES FOR CONTROLLED DELIVERY OF A THERAPEUTIC AGENT |
摘要 |
<p>The present invention is directed to novel implantable or insertable medical devices that provide controlled release of a therapeutic agent. According to an embodiment of the present invention, a therapeutic-agent-releasing medical device is provided, which comprises: (a) an implantable or insertable medical device; (b) a release layer disposed over at least a portion of the implantable or insertable medical device; and (c) a therapeutic agent. The release layer comprises a malefic anhydride polymer selected from (i) a malefic anhydride copolymer and (ü) a malefic anhydride graft polymer. The release layer regulates the rate of release of the therapeutic agent from the medical device upon implantation or insertion of the device into a patient. The present invention is also directed to methods of forming the above implantable or insertable medical devices, methods of administering a therapeutic agent to a patient using such devices, and methods of modulating the release of therapeutic agent from such devices.</p> |
申请公布号 |
WO2004000384(A1) |
申请公布日期 |
2003.12.31 |
申请号 |
WO2003US19269 |
申请日期 |
2003.06.19 |
申请人 |
SCIMED LIFE SYSTEMS, INC. |
发明人 |
SCHWARZ, MARLENE, C. |
分类号 |
A61K9/22;A61L27/34;A61L27/54;A61L29/08;A61L29/16;A61L31/10;A61L31/16;(IPC1-7):A61L31/10 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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