PROCESSES FOR PRODUCING EPOXYTRIAZOLE DERIVATIVE AND INTERMEDIATE THEREFOR

摘要

A compound represented by the following formula (I) is reacted with a trimethyloxosulfonium salt, etc. in the presence of a base to obtain a compound (II). The compound (II) is converted into a compound (IV). The compound (IV) is reacted with 1,2,4-triazole in the presence of a base. Thus , a high-quality epoxytriazole derivative (V) useful as an intermediate for antifungal agents and a high-quality intermediate for the derivative can be effectively produced at low cost by an industrial means. (In the formulae, A r represents phenyl optionally substituted with one to three halogen atoms or with trifluoromethyl; R represents hydrogen or lower alkyl; and X represents a leaving group.)