| 发明名称 |
Targeted chromosomal genomic alterations in plants using modified single stranded oligonucleotides |
| 摘要 |
Presented are methods and compositions for targeted chromosomal genomic alterations with modified single-stranded oligonucleotides. The oligonucleotides of the invention have modified nuclease-resistant termini comprising LNA, phosphorothioate linkages or 2'-O-Me base analogues or combinations of such modifications.
|
| 申请公布号 |
US2003236208(A1) |
申请公布日期 |
2003.12.25 |
| 申请号 |
US20020307005 |
申请日期 |
2002.11.26 |
| 申请人 |
KMIEC ERIC B.;GAMPER HOWARD B.;RICE MICHAEL C.;KIM JUNGSUP |
发明人 |
KMIEC ERIC B.;GAMPER HOWARD B.;RICE MICHAEL C.;KIM JUNGSUP |
| 分类号 |
A61K38/00;A61K48/00;C12N15/10;C12N15/113;C12N15/82;(IPC1-7):A61K48/00;C07H21/04;C12N15/85 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
