| 发明名称 |
NOVEL MAXI-K CHANNEL BLOCKERS, METHODS OF USE AND PROCESS FOR MAKING THE SAME |
| 摘要 |
This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions relate d to elevated intraocular pressure in the eye of a patient. This invention als o relates to the use of such compounds to provide a neuroprotective effect to the eye of a mammalian species, particularly humans.
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| 申请公布号 |
CA2488752(A1) |
申请公布日期 |
2003.12.24 |
| 申请号 |
CA20032488752 |
申请日期 |
2003.06.13 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
TKACZ, JAN S.;STROHL, WILLIAM R.;MONAGHAN, RICHARD L.;MCMANUS, OWEN B.;GARCIA, MARIA L.;GOETZ, MICHAEL A.;KACZOROWSKI, GREGORY J. |
| 分类号 |
C12P17/18;A61K9/08;A61K9/10;A61K31/407;A61K31/5575;A61K31/565;A61K45/00;A61K47/36;A61P25/00;A61P27/02;A61P27/06;C07D491/14;C07D491/18;C07D491/20;C07J73/00;C12R1/66;(IPC1-7):C07D487/22 |
主分类号 |
C12P17/18 |
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