发明名称 |
DERIVATIVES OF CHROMEN-2-ONE AS INHIBITORS OF VEGF PRODUCTION IN MAMMALIAN CELLS |
摘要 |
The compounds of formula (I) wherein A and R1-R5 are as defined in the description, are inhibitors of Vascular Endothelial Growth Factor and are useful as angiogenesis inhibitors and antiproliferative agents.
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申请公布号 |
WO03105842(A1) |
申请公布日期 |
2003.12.24 |
申请号 |
WO2003EP06191 |
申请日期 |
2003.06.12 |
申请人 |
NOVUSPHARMA S.P.A.;MENTA, ERNESTO;DA RE, GIOVANNI;GRUGNI, MARIO |
发明人 |
MENTA, ERNESTO;DA RE, GIOVANNI;GRUGNI, MARIO |
分类号 |
A61K31/415;A61K31/4164;A61K31/42;A61K31/4245;A61K31/425;A61K31/433;A61K31/435;A61P9/00;A61P35/00;(IPC1-7):A61K31/42;A61K31/424;A61K31/416 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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