| 摘要 |
Compounds of Formula I, wherein R1-R8 are defined herein are provided, together with pharmaceutically acceptable salts, hydrates, metabolites, and/or prodrugs thereof. Uses of these compounds for inhibiting beta amyloid production and for the prevention and treatment of Alzheimer's Disease and Down's syndrome are described.
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| 申请人 |
WYETH;ARQULE, INC.;KREFT, ANTHONY, FRANK;COLE, DEREK, CECIL;WOLLER, KEVIN, ROGER;STOCK, JOSEPH, RAYMOND;KUTTERER, KRISTINA, MARTHA;KUBRAK, DENNIS, MARTIN;MANN, CHARLES, WILLIAM;MOORE, WILLIAM, JAY;CASEBIER, DAVID, SCOTT |
发明人 |
KREFT, ANTHONY, FRANK;COLE, DEREK, CECIL;WOLLER, KEVIN, ROGER;STOCK, JOSEPH, RAYMOND;KUTTERER, KRISTINA, MARTHA;KUBRAK, DENNIS, MARTIN;MANN, CHARLES, WILLIAM;MOORE, WILLIAM, JAY;CASEBIER, DAVID, SCOTT |
