| 发明名称 |
NANOPARTICULATE FORMULATIONS COMPRISING HMG COA REDUCTASE INHIBITOR DERIVATIVES (STATINS), NOVEL COMBINATIONS THEREOF AS WELL AS MANUFACTURING OF THESE PHARMACEUTICAL COMPOSITIONS |
| 摘要 |
The present invention is directed to nanoparticulate compositions comprising statin such as lovastatin or simvastatin including surface stabilizer. The statin particles of the composition have an effective average particle size of less than about 2000 nm. In another aspect of this invention, novel combinations of statins and other cholesterol lowering agents are described and methods of using same are taught.
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| 申请公布号 |
CA2488499(A1) |
申请公布日期 |
2003.12.18 |
| 申请号 |
CA20032488499 |
申请日期 |
2003.06.10 |
| 申请人 |
ELAN PHARMA INTERNATIONAL LIMITED |
发明人 |
LIVERSIDGE, GARY G.;COOPER, EUGENE R.;RYDE, TUULA;LIVERSIDGE, ELAINE;LINDNER, MARIE;HOVEY, DOUGLAS;CAREY, GRETA |
| 分类号 |
A61K9/06;A61K9/10;A61K9/107;A61K9/14;A61K9/19;A61K9/20;A61K9/48;A61K9/72;A61K31/045;A61K31/185;A61K31/216;A61K31/22;A61K31/221;A61K31/34;A61K31/366;A61K31/381;A61K31/40;A61K31/4025;A61K31/405;A61K31/4155;A61K31/4164;A61K31/44;A61K31/455;A61K31/575;A61K31/661;A61K31/662;A61K31/717;A61K45/00;A61K45/06;A61K47/02;A61K47/04;A61K47/08;A61K47/10;A61K47/12;A61K47/14;A61K47/18;A61K47/20;A61K47/22;A61K47/24;A61K47/26;A61K47/28;A61K47/32;A61K47/34;A61K47/36;A61K47/38;A61K47/42;A61K47/44;A61P1/18;A61P3/06;A61P9/00;A61P9/08;A61P9/10;A61P25/28;A61P41/00;A61P43/00;(IPC1-7):A61K9/51;A61K9/16;A61K31/402;A61K31/416 |
主分类号 |
A61K9/06 |
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