VORRICHTUNG ZUR VERBESSERUNG DER TRANSDERMALEN VERABREICHUNG VON MEDIKAMENTEN ODER DER ABNAHME VON KÖRPERFLÜSSIGKEITEN

摘要

A minimally invasive transdermal agent sampling device (2, 10) comprises a sheet (6) having a plurality of openings (8) and a plurality of microblades (4) for piercing the skin (20). A suction device (10) applies a negative pressure through the openings (8) to the microslits in the skin (20) for enhanced efflux of interstitial fluid. The device (2, 10) can be used for transdermal sampling of body analytes such as glucose for measuring/estimating blood glucose concentration.