发明名称 |
Anti-CCR5 antibody |
摘要 |
The invention is directed an anti-CCR5 antibody which comprises (i) two light chains, each light chain comprising the expression product of a plasmid designated pVK:HuPRO140-VK (ATCC Deposit Designation PTA-4097), and (ii) two heavy chains, each heavy chain comprising an expression product of either a plasmid designated pVg1:HuPRO140 HG2-VH (ATCC Deposit Designation PTA-4098) or a plasmid designated pVg1:HuPRO140 (mutB+D+I)-VH (ATCC Deposit Designation PTA-4099) or a fragment thereof which binds to CCR5 on the surface of a human cell.
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申请公布号 |
US2003228306(A1) |
申请公布日期 |
2003.12.11 |
申请号 |
US20030371483 |
申请日期 |
2003.02.21 |
申请人 |
OLSON WILLIAM C.;MADDON PAUL J.;TSURUSHITA NAOYA;HINTON PAUL R.;VASQUEZ MAXIMILIANO |
发明人 |
OLSON WILLIAM C.;MADDON PAUL J.;TSURUSHITA NAOYA;HINTON PAUL R.;VASQUEZ MAXIMILIANO |
分类号 |
C07K16/28;(IPC1-7):A61K39/395;C12P21/04 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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