| 发明名称 |
COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES SUCH AS ALZHEIMER'S DISEASE, TYPE 2 DIABETES, AND PARKINSON'S DISEASE |
| 摘要 |
<p>Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially A.szlig. amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinophathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.</p> |
| 申请公布号 |
CA2486869(A1) |
申请公布日期 |
2003.12.11 |
| 申请号 |
CA20032486869 |
申请日期 |
2003.05.30 |
| 申请人 |
PROTEO TECH, INC. |
发明人 |
SNOW, ALAN D.;NGUYEN, BETH P.;CASTILLO, GERARDO M.;WEAVERS, REX T.;LARSEN, LESLEY;LORIMER, STEPHEN D.;SANDERS, VIRGINIA J.;LAKE, THOMAS P.;LARSEN, DAVID S.;COFFEN, DAVID L. |
| 分类号 |
C07D295/08;A61K31/05;A61K31/121;A61K31/137;A61K31/165;A61K31/166;A61K31/167;A61K31/17;A61K31/4375;A61K31/439;A61K31/4418;A61K31/495;A61P3/10;A61P5/00;A61P25/00;A61P25/28;A61P35/00;A61P43/00;C07C37/055;C07C39/15;C07C39/16;C07C39/17;C07C45/62;C07C45/64;C07C45/65;C07C49/83;C07C49/835;C07C67/08;C07C67/14;C07C69/017;C07C69/157;C07C215/48;C07C215/50;C07C233/18;C07C233/25;C07C233/56;C07C235/34;C07C235/38;C07C235/48;C07C235/54;C07C235/56;C07C237/20;C07C237/22;C07C275/34;C07D213/85;C07D295/096;C07D295/18;C07D295/192;C07D451/06;C07D471/04;(IPC1-7):C07C49/83;C07D498/08;C07D231/06;C07D487/04;C07D207/16;C07D333/16;C07D213/84;C07D213/66;C07D213/30;C07D217/26;C07C43/23;C07D263/18 |
主分类号 |
C07D295/08 |
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