METHOD AND DEVICE FOR DIAGNOSING FUNCTIONAL STATE OF ORGANISM

摘要

FIELD: medicine; medical engineering. SUBSTANCE: method involves investigating blood oxygenation and deoxygenation kinetics by varying its optical properties in time using a device. Blood oxygenation (deoxigenation) processes are carried out many times in essentially small blood volume on sublayer enclosed in sealed thermostat chamber cavity filled with gas mixture having required partial oxygen pressure. Effective blood sample-gas mixture gas exchange is provided by periodically varying blood surface area making contact with gas environment and/or by renewing it using special purpose mechanism. Optical signal representing blood oxygen saturation is continuously recorded during the whole time the blood sample -gas mixture oxygen gas exchange takes place. Various states of blood sample under study are modeled by varying gas mixture composition filling the chamber. Functional organism state evaluation is carried out by comparing data received in modeling. Device has sealed wet-statically controlled chamber designed as cavity under cover closing thermostatically controlled blood sample sublayer on the upper wall of the device body. The cavity is attached to gas mixture supply system having composition control unit. The device has mechanism for renewing blood surface contact to gas mixture and varying area of the contact. Optical oximeter optically bound to blood sample is built in into the device body. The device has sublayer temperature-, working cavity pressure and humidity control systems. Gages for measuring each of the parameters are placed in working cavity and connected to the recorder. EFFECT: enhanced effectiveness in detecting organism functional state deviations from norm and restoring adaptation capability. 23 cl, 11 dwg