发明名称 |
AGGLOMERATED PARTICLES FOR AEROSOL DRUG DELIVERY |
摘要 |
The invention provides a drug delivery vehicle for inhalation by a patient. The drug delivery vehicle comprises biocompatible particles between 0.1 and 1.0 microns in diameter, that are loaded with one or more drugs and which are crosslinked together to form agglomerates. The agglomerates can also provide for delivery of contrast-enhancing agents for clinical imaging. The invention also provides methods of making the inventive agglomerates, pharmaceutical compositions comprising the agglomerates, and methods for delivering drugs or contrast-enhancing agents to a patient by inhalation of pharmaceutical compositions containing the agglomerates. |
申请公布号 |
WO03075977(A3) |
申请公布日期 |
2003.12.04 |
申请号 |
WO2003US06797 |
申请日期 |
2003.03.05 |
申请人 |
CLEVELAND STATE UNIVERSITY;ANNAPRAGADA, ANNANTH;BHAVANE, ROHAN |
发明人 |
ANNAPRAGADA, ANNANTH;BHAVANE, ROHAN |
分类号 |
A61K9/72;A61K9/00;A61K9/12;A61K9/127;A61K9/16;A61K9/26;A61K38/28;A61K47/44;A61K47/48;A61K49/00;A61P3/10 |
主分类号 |
A61K9/72 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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