发明名称 Cyclohexyl derivatives and their use as therapeutic agents
摘要 The present invention relates compounds of the formula (I): wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of: (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), (l) and R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<13>, R<14>, R<15>, R<16>, R?17, R<18>, R<19>, R<21a >and R<21b >are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia. <chemistry-cwu id="CHEM-US-00002"> <NUMBER>2</NUMBER> <image id="EMI-C00002" he="364.3542" wi="145.2087" file="US20030225059A1-20031204-C00002.TIF"/> <chemistry-chemdraw-file id="CHEMCDX-00002" file="US20030225059A1-20031204-C00002.CDX"/> <chemistry-mol-file id="CHEMMOL-00002" file="US20030225059A1-20031204-C00002.MOL"/> </CHEMISTRY-CWU>
申请公布号 US2003225059(A1) 申请公布日期 2003.12.04
申请号 US20020276129 申请日期 2002.11.13
申请人 PINEIRO JOSE LUIS CASTRO;DINNELL KEVIN;ELLIOTT JASON MATTHEW;HOLLINGWORTH GREGORY JOHN;SHAW DUNCAN EDWARD;SWAIN CHRISTOPHER JOHN;YANG LIHU 发明人 PINEIRO JOSE LUIS CASTRO;DINNELL KEVIN;ELLIOTT JASON MATTHEW;HOLLINGWORTH GREGORY JOHN;SHAW DUNCAN EDWARD;SWAIN CHRISTOPHER JOHN;YANG LIHU
分类号 C07D295/04;A61K31/075;A61K31/12;A61K31/135;A61K31/16;A61K31/165;A61K31/215;A61K31/341;A61K31/357;A61K31/40;A61K31/403;A61K31/41;A61K31/4164;A61K31/4196;A61K31/4355;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4453;A61K31/451;A61K31/472;A61K31/495;A61K31/496;A61K31/5375;A61K31/54;A61K31/55;A61P1/08;A61P25/04;A61P25/06;A61P25/22;A61P25/24;A61P29/00;A61P43/00;C07C43/178;C07C45/29;C07C49/497;C07C49/517;C07C49/697;C07C49/747;C07C49/753;C07C69/757;C07C69/767;C07C217/48;C07C217/52;C07C229/22;C07C233/23;C07C233/31;C07C233/32;C07C233/58;C07C233/59;C07C235/40;C07C235/80;C07C235/82;C07C237/04;C07C237/08;C07C237/24;C07D207/06;C07D207/16;C07D211/14;C07D211/18;C07D211/22;C07D211/38;C07D211/42;C07D211/46;C07D211/48;C07D211/58;C07D211/62;C07D211/70;C07D211/74;C07D213/38;C07D217/04;C07D233/90;C07D241/08;C07D257/04;C07D265/30;C07D275/04;C07D277/28;C07D295/08;C07D295/096;C07D295/14;C07D295/15;C07D295/155;C07D295/185;C07D295/192;C07D295/205;C07D307/52;C07D317/72;C07D333/20;C07D401/04;C07D401/06;C07D413/04;C07D417/12;C07D487/08;C07D491/20;(IPC1-7):A61K31/55;A61K31/541;A61K31/537;A61K31/454;A61K31/443;C07D417/02;C07D413/02;C0743/02;C0741/02 主分类号 C07D295/04
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