| 摘要 |
The present invention relates to compositions and methods for preventing, treating or delaying viral myocarditis or dilated (congestive) cardiomyopathy (DCM) in mammals, particularly humans. More particularly, the present invention provides for methods for preventing, treating or delaying viral myocarditis or dilated (congestive) cardiomyopathy (DCM) in a mammal, which method comprises administering to a mammal, to which such prevention, treatment or delay is needed or desirable, an effective amount of a neuregulin protein, or a functional fragment thereof, or a nucleic acid encoding a neuregulin protein, or a functional fragment thereof, or an agent that enhances production and/or function of said neuregulin, whereby said viral myocarditis or DCM is prevented, treated or delayed. Combinations, kits and pharmaceutical compositions for preventing, treating or delaying viral myocarditis or dilated (congestive) cardiomyopathy (DCM) in mammals using neuregulins and their enhancers are also provided. |
