发明名称 CALCIUM RECEPTOR MODULATING AGENTS
摘要 The compounds of the invention are represented by the following general structure (I) or a pharmaceutically acceptable salt thereof, and composition s containing them, wherein the variables are defined herein, and their use to reduce or inhibit PTH secretion, including methods for reducing or inhibitin g PTH secretion and methods for treatment or prophylaxis of diseases associate d with bone disorders, such as osteoporosis, or associated with excessive secretion of PTH, such as hyperparathyroidism. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
申请公布号 CA2485685(A1) 申请公布日期 2003.12.04
申请号 CA20032485685 申请日期 2003.05.23
申请人 AMGEN, INC. 发明人 TOWNSEND, ROBERT;XU, SHIMIN;KELLY, MICHAEL G.;XI, NING;GHIRON, CHIARA;COULTER, THOMAS;SEMIN, DAVID J.
分类号 C07D249/18;A61K31/403;A61K31/404;A61K31/407;A61K31/4178;A61K31/4184;A61K31/4192;A61K31/422;A61K31/437;A61K31/4439;A61P5/20;A61P19/10;A61P43/00;C07D209/08;C07D209/10;C07D209/12;C07D209/80;C07D209/86;C07D209/88;C07D235/06;C07D235/08;C07D249/04;C07D401/04;C07D403/04;C07D413/04;C07D471/04;C07D491/04;C07D491/052;(IPC1-7):C07D413/04 主分类号 C07D249/18
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