摘要 |
<p>The invention relates to the field of immunology, gene therapy and medicine. More specifically, the invention relates to the identification of a molecule capable of interacting with a soluble and/or cell bound form of CD163 and as a result of said interaction an immune response is either instigated or suppressed in an organism. Furthermore it relates to the preparation of a pharmaceutical composition comprising said molecule and/or antagonist I and/or agonist I thereof, and/or an isolated CD163 and/or an antagonist II or agonist II thereof, for the therapeutic or prophylactic treatment of an individual with an immune response disorder, e.g. inflammation, cancer, or infection.</p> |
申请人 |
BIOCEROS B.V. I.O.;MACROZYME B.V.;BOON, LOUIS;SIMONS, PETRUS, JOHANNES;SPEIJER, DAVID;VAN NEERVEN, RUPRECHT, JULES, JOOST |
发明人 |
BOON, LOUIS;SIMONS, PETRUS, JOHANNES;SPEIJER, DAVID;VAN NEERVEN, RUPRECHT, JULES, JOOST |