发明名称 |
Modified transferrin fusion proteins |
摘要 |
Modified fusion proteins of transferrin and therapeutic proteins or peptides including soluble toxin receptors, with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor.
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申请公布号 |
US2003221201(A1) |
申请公布日期 |
2003.11.27 |
申请号 |
US20030378094 |
申请日期 |
2003.03.04 |
申请人 |
BIOREXIS PHARMACEUTICAL CORPORATION |
发明人 |
PRIOR CHRISTOPHER P.;LAI CHAR-HUEI;SADEGHI HOMAYOUN;TURNER ANDREW |
分类号 |
A61K38/00;A61K47/48;C07K7/06;C07K7/08;C07K14/705;C07K14/79;(IPC1-7):A61K38/21;A61K38/40;A01K67/027 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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