发明名称 |
GLP-1 gene delivery for the treatment of type 2 diabetes |
摘要 |
This patent discloses compositions and methods of use thereof to normalize the blood glucose levels of patients with type 2 diabetes. It relates particularly to a plasmid comprising a chicken beta actin promoter and enhancer; a modified GLP-1 (7-37) cDNA (pbetaGLP1), carrying a furin cleavage site, which is constructed and delivered into a cell for the expression of active GLP-1.
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申请公布号 |
US2003220274(A1) |
申请公布日期 |
2003.11.27 |
申请号 |
US20020153470 |
申请日期 |
2002.05.21 |
申请人 |
EXPRESSION GENETICS INC |
发明人 |
OH SEUNGJOON;LEE MINHYUNG;KO KYUNGSOO |
分类号 |
A61K38/00;A61K47/48;A61K48/00;C07K14/605;(IPC1-7):A61K48/00;C12N15/85 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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