发明名称 |
Clavulanic acid dehydrogenase, preparation and use for the production of clavulanic acid |
摘要 |
An isolated DNA fragment encoding a protein with CAD activity wherein the protein is clavulanic acid dehydrogenase (CAD) from S. clavuligerus, with the proviso that the isolated DNA fragment is not: (a) the 13.1 kb BglII to SphI fragment of S. clavuligerus; (b) the 10.8 kb EcoRI to BamHI fragment of S. clavuligerus; (c) the 8.8 kb BclI to BclII fragment of S. clavuligerus; (d) the 2.5 kb BglII to BglII fragment of S. clavuligerus; (e) the 60 kb BglII to BamHI fragment of S. clavuligerus; or (f) the 18.0 BclI to SphI fragment of S. clavuligerus.
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申请公布号 |
US2003219867(A1) |
申请公布日期 |
2003.11.27 |
申请号 |
US20030367221 |
申请日期 |
2003.02.14 |
申请人 |
SMITHKLINE BEECHAM PLC |
发明人 |
ARNELL JANICE;ELSON STEPHEN WILLIAM;NICHOLSON NEVILLE HUBERT;WORONIECKI STEFAN ROLAND |
分类号 |
C07D503/00;C12N1/21;C12N9/04;C12P17/18;(IPC1-7):C12P17/16;C12N9/06;C07H21/04;C12P21/02;C12N15/74 |
主分类号 |
C07D503/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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