| 摘要 |
<p>The present invention provides biodegradable cationic liposomes of a mixture of a cationic lipid and a neutral lipid, cationic liposome compositions, and methods of using same for the controlled release of a biologically active substance to a specified tissue or cells. Preferred cationic lipids for use in cationic liposomes include cationic lipids having a positively charged group and two hydroxyl groups which are capable of complexing one or more biologically active substances. Preferred methods include the controlled release of biologically active substances and gene therapy using cationic liposomes and compositions composed thereof.</p> |
