| 发明名称 |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF GRAFT FAILURE |
| 摘要 |
The present invention provides methods and compositions for treating graft failure resulting from neointimal hyperplasia. These methods and compositions feature the use of platelet derived growth factor receptor (PDGFR) inhibitor compounds, such as N-phenyl-2-pyrimidine compounds (e.g., imatinib mesylate) to inhibit the biological activity of the PDGFR.
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| 申请公布号 |
WO03094904(A1) |
申请公布日期 |
2003.11.20 |
| 申请号 |
WO2003US14916 |
申请日期 |
2003.05.13 |
| 申请人 |
BETH ISRAEL DEACONESS MEDICAL CENTER;SUKHATME, VIKAS, P. |
发明人 |
SUKHATME, VIKAS, P. |
| 分类号 |
C07D401/04;A61K31/165;A61K31/436;A61K31/505;A61K31/506;A61K31/5415;A61K45/00;A61K45/06;A61L33/00;A61P7/02;A61P9/10;A61P43/00;(IPC1-7):A61K31/165;A61K38/21 |
主分类号 |
C07D401/04 |
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