发明名称 Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols
摘要 Compositions comprising (±)-2-((dimethylamino)methyl)cyclohexanone, a transition-metal salt, and an organic solvent and methods of preparing (±)-cis-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols, in particular (±)-cis-2-((dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanol, are disclosed herein. In one embodiment, the (±)-2-((dimethylamino)methyl)cyclohexanone and transition-metal salt are in the form of a (±)-2-((dimethylamino)methyl)cyclohexanone:transition-metal salt complex. In another embodimemt, aryl is 3-methoxyphenyl.
申请公布号 US6649783(B2) 申请公布日期 2003.11.18
申请号 US20010968855 申请日期 2001.10.03
申请人 EURO-CELTIQUE, S.A. 发明人 KUPPER ROBERT J.;STUMPF ANDREAS
分类号 C07C213/00;C07C213/02;C07C217/74;C07C225/12;C07F15/02;(IPC1-7):C07F15/02;C07F3/00;C07F13/00;C09K3/00;A61K31/28 主分类号 C07C213/00
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