| 摘要 |
A platelet function assay reagent is provided for performing a platelet function assay, wherein the reagent contains a mixture of magnetic and non-magnetic particles, wherein the magnetic particles have bound to an outer surface thereof an amount of a first ligand having an affinity for direct interaction with GP-Ib receptors on blood platelets and wherein the non-magnetic particles have bound to an outer surface thereof an amount of a second ligand having an affinity for direct interaction with GP-Ib receptors on blood platelets, such that interaction of either of the first or second ligands with the GP-Ib platelet receptor will activate the blood platelets toward aggregation, wherein the first ligand and the second ligand can be the same or different, and the assay using such reagent, for providing a fast, reliable point-of-care assessment of platelet function.
|
