发明名称 |
Methods and compositions for identifying ligands for nuclear receptors |
摘要 |
A yeast-based system and methods of use therefore are provided for identifying new molecules which activate nuclear receptors in a ligand-dependent fashion. In a preferred embodiment, a method is provided utilizing ecdysone receptor, USP and GRIP I encoding expression vectors which may be used to advantage for screening new and useful insecticidal compounds, detecting insecticidal residues as well as to regulate expression of a gene of interest in a host in a ligand-dependent manner.
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申请公布号 |
US2003211455(A1) |
申请公布日期 |
2003.11.13 |
申请号 |
US20020204169 |
申请日期 |
2002.12.02 |
申请人 |
TRAN HIEP TUAN;SHAABAN SALAM;ASKARI HOSSEIN;SCHWARTZ MICHAEL;BUTT TAUSEEF |
发明人 |
TRAN HIEP TUAN;SHAABAN SALAM;ASKARI HOSSEIN;SCHWARTZ MICHAEL;BUTT TAUSEEF |
分类号 |
A61K31/00;C12N15/10;C12Q1/68;(IPC1-7):A61K31/00;C12Q1/00;C12N1/18;C12N5/06 |
主分类号 |
A61K31/00 |
代理机构 |
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地址 |
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