发明名称 |
COMPOSITIONS AND METHODS FOR DETERMINING SUSCEPTIBILITY OF HEPATITIS C VIRUS TO ANTI-VIRAL DRUGS |
摘要 |
The present invention provides methods for determining the susceptibility of a pathogenic flavivirus to anti-viral compounds. This invention also provides methods for determining anti-viral drug susceptibility in a patient infected with a flavivirus. This invention also provides a method for evaluating the biological effectiveness of a candidate anti-viral drug compound. The methods are useful for identifying effective drug regimens for the treatment of flaviviral infections, and identifying and assessing the biological effectiveness of potential therapeutic compounds. Compositions including resistance test vectors and host cells transformed with the resistance test vectors are provided. |
申请公布号 |
WO03093492(A2) |
申请公布日期 |
2003.11.13 |
申请号 |
WO2003US13791 |
申请日期 |
2003.05.05 |
申请人 |
VIROLOGIC, INC. |
发明人 |
PARKIN, NEIL, T.;GAMARNIK, ANDREA |
分类号 |
C07K14/18;C12N15/51;C12N15/85;C12N15/86;C12Q1/68;C12Q1/70 |
主分类号 |
C07K14/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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