发明名称 |
Infectious papillomavirus pseudoviral particles |
摘要 |
The invention provides an infectious papillomavirus pseudoviral particle useful in gene transfer comprising: (a) a papillomavirus vector DNA which comprises an E2 binding site and an expression cassette comprising a gene and a sequence controlling expression of said gene; and (b) a papillomavirus capsid which comprises L1 and L2 structural proteins, such that said capsid encapsidates said vector DNA, wherein said gene is derived from a first biological species and said L1 structural protein is derived from a second biological species and said first biological species is different from said second biological species.
|
申请公布号 |
US2003207446(A1) |
申请公布日期 |
2003.11.06 |
申请号 |
US20030446060 |
申请日期 |
2003.05.27 |
申请人 |
LOWY DOUGLAS R.;SCHILLER JOHN T.;RODEN RICHARD B. |
发明人 |
LOWY DOUGLAS R.;SCHILLER JOHN T.;RODEN RICHARD B. |
分类号 |
G01N33/50;A61K35/76;A61K38/43;A61K38/45;A61K39/00;A61K48/00;A61P7/04;A61P17/00;A61P35/00;C07K14/025;C07K16/08;C12N1/15;C12N5/10;C12N7/00;C12N7/04;C12N15/09;C12N15/37;C12N15/86;C12Q1/70;G01N33/15;(IPC1-7):A61K48/00 |
主分类号 |
G01N33/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|