发明名称 |
ENHANCEMENT OF HUMAN EPIDERMAL MELANOGENESIS |
摘要 |
The invention provides methods and compositions that promote sunless tanning in human skin using a MAPK pathway inhibitor, particularly, a MEK-inhibitor, which induces melanogenesis in epidermal melanocytes alone or in combination with a cAMP-elevating agent. The compositions are preferably administered topically to the skin. |
申请公布号 |
WO03090688(A2) |
申请公布日期 |
2003.11.06 |
申请号 |
WO2003US12825 |
申请日期 |
2003.04.24 |
申请人 |
VAN ANDEL INSTITUTE;KOO, HAN-MO;VANDE WOUDE, GEORGE;VANBROCKLIN, MATT;EISENMANN, KATHRYN |
发明人 |
VANDE WOUDE, GEORGE;VANBROCKLIN, MATT;EISENMANN, KATHRYN |
分类号 |
A61K8/44;A61K8/49;A61K8/64;A61K38/48;A61Q19/04;C12N9/00 |
主分类号 |
A61K8/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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