发明名称 DERIVATIVES OF AMINOALKANE SULPHONIC, PHOSPHONIC AND PHOSPHINIC ACIDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
摘要 Derivatives of sulphonic aminoalkane acids, corresponding to formula (I)where X is R1, R2 and R3 are selected from hydrogen and a C1-C7 alkyl radical, and A is a group of the formula (e) where v and w are 0, 1, 2 or a group of formula (f) where R5 and R6 are selected independently of each other from hydrogen, a C1-C7 alkyl radical, an aryl radical having between 6 and 14 carbon atoms and a heteroaryl radical; t is 1-3; R4 is selected from hydrogen, a C1-C7 alkyl radical, a CF3 radical, an aryl radical having between 6 and 14 carbon atoms and a heteroaryl radical; M is a monovalent metal (Na, K, Li) or a divalent metal (Ca, Mg, Sr, Zn); m is 1 or 2; p is 1-2 and q is 1-2; and where p and q are such that the electrical neutrality of the salt is ensured. The compounds can be used for the treatment of alcohol dependence.
申请公布号 DE69818709(D1) 申请公布日期 2003.11.06
申请号 DE1998618709 申请日期 1998.01.27
申请人 MERCK SANTE, LYON 发明人 BERTHELON, JEAN-JACQUES;DURBIN, PHILIPPE
分类号 A61K31/662;A61K31/185;A61K31/66;A61P25/32;C07C309/15;C07C309/24;C07F9/30;C07F9/38;(IPC1-7):C07C309/15 主分类号 A61K31/662
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