| 摘要 |
The present invention concerns chemical and biological assays that employ electrochemiluminescence (ECL), also referred to as electrogenerated chemiluminescence. More particularly, the present application pertains to certain classes of chemical moieties that strongly quench ECL, and to the use of these ECL quenchers in combination with ECL labels, for example, in ECL assay methods that employ an ECL quencher and an ECL label. One class of such quenching moieties are those that comprise at least one benzene moiety. Sub-classes of such quenching moieties are those that comprise at least one phenol moiety, quinone moiety, benzene carboxylic acid, and/or at least one carboxylate moiety. <IMAGE> |
