发明名称 |
Heteroaryl-phenyl derivatives as factor xa inhibitors for use as antithrombotic and anticoagulant agents |
摘要 |
The invention relates to heterocyclic derivatives of formula (I) A-B-X<1>-T<1>(R<2>)-L<1>-T<2>(R<3>)-X<2>-Q where the variables are defined in the specification, or pharmaceutically-acceptable salts thereof, which possess antithrombotic and anticoagulant properties and are accordingly useful in methods of treatment of humans or animals. The invention also relates to processes for the preparation of the heterocyclic derivatives, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments for use in the production of an antithrombotic or anticoagulant effect.
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申请公布号 |
EP1358909(A1) |
申请公布日期 |
2003.11.05 |
申请号 |
EP20030011815 |
申请日期 |
1997.11.04 |
申请人 |
ASTRAZENECA AB |
发明人 |
PRESTON, JOHN;STOCKER, ANDREW;TURNER, PAUL;SMITHERS, MICHAEL JAMES;RAYNER, JOHN WALL |
分类号 |
A61K31/44;A61K31/444;A61K31/496;A61K31/501;A61K31/505;A61K31/506;A61P7/02;C07D213/00;C07D213/56;C07D213/61;C07D213/73;C07D213/84;C07D213/89;C07D237/08;C07D239/26;C07D241/00;C07D307/77;C07D401/10;C07D405/12;(IPC1-7):A61P7/02;C07D403/10 |
主分类号 |
A61K31/44 |
代理机构 |
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